Diabetic foot ulcer is one of the major complications of Diabetes Mellitus and this leads to amputation of the concerned portion in at least 85% cases. The major reason of mortality in such cases is due to the complications developed in vascular regions both major and minor. Diabetes impairs the ability of the body to grow new tissues as it prevents the flow of oxygen to the tissue.
This is due to the inflammation of the wound and as such causes swelling of the region inhabiting repair.Granulation tissue formation is prevented and there is a lose in wound tensile strength in patients suffering from diabetes. The major risk factors include smoking, heavy drinking and other factors related to smoking.